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These pioneering studies suggest targeting HDACs shows promise in the treatment of epilepsy

To elucidate the specific role of each putative binding site, we generated constructs with mutations in the P65 binding motif 1 (MutA), motif 2 (MutB), or both (MutAB) (Fig

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When necessary, the membranes were stripped by shaking them for 60 min at 37 C in 67 mM Tris (pH 6.7), 2% SDS, and 100 mM -mercaptoethanol and reprobed with an appropriate pan-antibody

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