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Manuscript source: Unsolicited manuscript Peer-review started: February 13, 2020 First decision: March 26, 2020 Article in press: September 10, 2020 Specialty type: Gastroenterology and hepatology Country/Territory of origin: Croatia Peer-review reports scientific quality classification Grade A (Excellent): 0 Grade B (Very good): B Grade C (Good): 0 Grade D (Fair): 0 Grade E (Poor): E P-Reviewer: Akyol C, Wang K S-Editor: Zhang L L-Editor: A P-Editor: Li JH Contributor Information Lidija Berkopic Cesar, Department of Pharmacology, School of Medicine, University of Zagreb, Zagreb 10 000, Croatia