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13,71,72 In small defects, where initial damage is limited, posttraumatic loading aggravates DD, because it maintains a high level of inflammation and catabolism

Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin-17A production

British Journal of Haematology 1979;42(4) 547-555 75

Ito cell tumorlarger and more extensive than hyperplasia

NFS1 degrades cysteine and releases sulphide, which can be used to generate ironsulphur (FeS) clusters, 138 versatile co-factors that carry out electron transfer, catalysis and afford structural stability