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Blood samples for analysis of serum B12 should be protected from light during collection, and whole blood separated as soon as possible as delays in centrifugation and separation can lead to an initial rise in serum B12 concentrations (Allen et al, 2018)

The rarity of folate deficiency is consistent with recent data from the United States and Canada, pointing to the introduction of widespread folic acid fortification of many foods

Ensuring sufficient B12 intake through diet or supplements is vital

6 to 8 weeks after can be observed to strengthen haematogenous function

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