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Similar to TRPA1 (Takahashi et al., 2011) and TRPM2 (Mei et al., 2006

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This interferes with the carboxylation and activation of vitamin K-dependent clotting factors, factors II, IV, IX, and X (Figure 21-1)

These include the ability to suppress or eliminate harmful bacteria, balance the intestinal microecology, promote digestion and nutrient absorption, improve the intestinal environment, stimulate immune cell function, and strengthen the bodys immune response ( 4.3.2 Mechanism of action in dry eye disease Recent studies have advanced our understanding of the ocular surface microbiota, identifying key bacterial groups such as Firmicutes (such as Staphylococcus and Streptococcus ), Actinomycetes (specifically Corynebacterium ), and Proteobacteria (including Acinetobacter and Pseudomonas )

Gentle Cleansing: Offers a mild yet effective cleansing experience, suitable for all skin types