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Through the selective clearance of damaged mitochondria, mitophagy reduces the production of ROS, thereby protecting cells from oxidative damage [16]

Abstract c-MET is a receptor tyrosine kinase that, after binding with its ligand, hepatocyte growth factor, activates a wide range of different cellular signaling pathways, including those involved in proliferation, motility, migration and invasion

Furthermore, GA enhanced endothelial function, inhibited platelet aggregation and thrombosis, reduced abnormal vascular smooth muscle cell proliferation, and stabilized atherosclerotic plaques, comprehensively addressing the pathological processes of ASCVD

Aging Cell 18 (6), e13034

Validation of early human dose prediction: a key metric for compound progression in drug discovery