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Blocking FOXO4, which inhibits the activation of P53, causes senescent cells to undergo apoptosis by P53 activation, without affecting healthy cells around them, and has anti-aging effects which may have potential applications in the treatment of numerous age-related diseases, as well as an adjunct to treatment for certain forms of cancer

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doi: 10.1016/j.saa.2023.123787 129 La CeciliaD.DaxA.EhmannH.KosterM.SingerH.StammC

Het lichaam maakt er zelf veel aan, als neuromodulatoren , als hormonen, als signaalmoleculen