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In preclinical research, chronic AOD-9604 significantly reduced body-weight gain and increased fat oxidation and lipolysis in obese mice[1][2]

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Figure 5 In addition to assessing cell viability, DNA damage was visualized by PI (45, 46) and Hoechst staining of Th- MYCN spheres following exposure to M+D and M+D+V combinations ( Supplementary Figure S2 )