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Biomedicines 11(7):1964 Shokri M et al (2021) Adjuvant use of melatonin for relieving symptoms of painful diabetic neuropathy: results of a randomized, double-blinded, controlled trial

7.2 Scale-up and industrial translation Although many nanoformulations have shown success at the laboratory scale, industrial translation remains limited due to complex synthesis routes, cost-intensive materials, and batch-to-batch variability