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Adenosine is either deaminated to inosine or used in the synthesis of nucleotides by salvage pathway 2

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This metabolic switching is regulated by sirtuins, namely SIRT3 and SIRT2 repress the Warburg effect 342345 , while SIRT5 maintains glycolysis 346

This design integrates homotypic tumor targeting (conferred by the cancer cell membrane cloak) with mitochondrial targeting (TPP) (Figure 12)

Glutaredoxins regulate maize inflorescence meristem development via redox control of TGA transcriptional activity