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doi: 10.1038/s41572-024-00589-9 9 YangKZengLZengJDengYWangSXuHet al

5 Stem cells in intervertebral disc repair The most important pathological features of IVDD include metabolic imbalance of proteoglycans and type II collagen in the extracellular matrix (ECM), and a reduction in the number of nucleus pulposus cells (NPCs) (Xin et al., 2022)

Enucleated reticulocytes lose their organelles to become mature erythrocytes, superspecialized cells deprived of organelles to accommodate more oxygen-transporting hemoglobin