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Preclinical studies in rodent models demonstrated increased fat oxidation and reduced adiposity without measurable changes in IGF-1 or blood glucose (Ng and Bornstein, 2000

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Animal Model:Diet induced obese (DIO) C57Bl6 mice [1] Dosage:30 mg/kg Administration:Orally once Result:NAD levels were significantly increased at both the 2 and 6 h time points in liver and muscle

Although these strategies improved the outcome of MM patients, the majority of them still relapse and have a poor prognosis [36]