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Results Summary: While early Phase 2 trials showed promising functional improvements (EX: increased distance walked in the 6 minute walk test in PMM patients), large Phase 3 trials have been complex and have sometimes failed to meet primary endpoints, underscoring the challenge of treating complex mitochondrial disorders

Most people notice initial improvements in skin hydration and hair texture within 4-6 weeks of consistent supplementation

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Moreover, and this is a little-known fact, although the production of melanin is very beneficial in protecting our skin from the sun, it is not without risks and consequences for the cell that produces it (TOBIN, 2008)