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In recent years, the importance of hypoxic microenvironment in the pathogenesis of RA has gradually attracted attention

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L-thyroxine administration has demonstrated efficacy in over 50% of cases involving thyroid peroxidase antibody syndrome ( In addition, preimplantation genetic testing for aneuploidy is often performed, though it remains controversial whether this decreases the risk of RM (Table 2

Histopathologically, psoriasis is characterized by infiltration of immune cells, epidermal hyperproliferation, and abnormal keratinocyte (KC) differentiation (9)