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Gaus, M., Goez, A

doi:10.1200/JCO.2005.03.3266

ZhangMViennoisEPrasadMZhangYWangLZhangZet al

Subsidiary analyses involved dominant and recessive genetic models, where possible

Alternatively, N -glucuronidation at the N 2 - or 3-positions of HCA or OH- N -HCA, mainly catalysed by uridine diphosphate (UDP)glucuronosyltransferases in the liver, competes with the activation pathway and results in the formation of inactive glucuronide conjugates including HCA- N 2 - -D-glucuronide (HCA-G), HCA-3- -D-glucuronide, OH- N -HCA-G, and OH- N -HCA-3- -D-glucuronide [8,9,10,11]