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A deeper insight into these regulatory mechanisms will be essential to exploit emerging imaging capabilities for early diagnostics and, ultimately, for the development of truly causal and precision-based therapeutic approaches targeting neurovascular dysfunction

This suggests the MTHFR C677T mutation is a genetic risk factor of IS, and primary and secondary prevention should be initiated in a timely manner in population with this mutation

Mercaptoacetic acid was dimerized in the presence of trifluoroacetic acid and acetone and then reduced with lithium aluminum hydride into the linker 2,2-(propane-2,2-diylbis(sulfanediyl))diacetic acid (synthetic strategy: Supplementary Fig

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(5188:) Pyruvate kinase isozymes R/L (R-type/L-type pyruvate kinase) (Redcell/liver pyruvate kinase) (Pyruvate kinase 1)