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Update 26 (2), 247263

There are 500mg of l-carnosine per serving

Histamine influences the expression of the interleukin-6 receptor on human lymphoid, monocytoid and hepatoma cell lines

Additionally, this can cause astrocytic swelling, which leads to channel opening that has been associated with astrocytic release of glutamate, which would further support excitotoxicity (Kimelberg et al., 1990)