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Primarily, these substances showcase notable neuroprotective effects, crucial for preserving neuronal integrity and function amidst the pathological processes underlying neurodegeneration

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OX contributes to the reduction of activation threshold in DRG neurons, particularly due to the sensitivity of TRPV1s from the vanilloid subfamily ( It is well known that the numerous TRP channels processed in several cell types use cysteine residues to detect changes in redox states

Notably, knocking-down DNA-PKcs had minimal impact on the expression of mitophagy-related proteins p62, LC3B, Pink1, and Beclin1 (Fig