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Out of the 115 genes known to be involved in the oxidative stress response (Worm Base gene ontology term GO:0006979), only one hypothetical thioredoxine-like gene ( W01B11.6 ) was modestly induced by glucose

Conversely, age-related downregulation of antioxidant enzymes (e.g., catalase and SODs) triggers a vicious cycle of impaired H 2 O 2 scavenging, further exacerbating mtROS damage [299, 300]

Bojkowski, C

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AG and KC have filed a patent on the use of a dual receptor antagonist of thromboxane A2 /TP and PGD2DP2 receptors for treatment of maladaptive immune response or thrombotic diathesis