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Butyrate inhibits NF-B activation in lamina propria macrophages of patients with ulcerative colitis

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Its level can be downregulated when breast cancer or renal cancer patients receive RTK-targeted therapy or HER2 + breast cancer cells receive trastuzumab treatment, resulting in an increased resistance to drugs 34

5 Conclusion The potential therapeutic impact of RY-A on CCH and its mechanism was examined using an integrated approach combining serum pharmacochemistry, metabolomics, and transcriptomics, with verification through animal experiments