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Comparison of buprenorphine and methadone in the treatment of opiate withdrawal: possible advantages of buprenorphine for the treatment of opiate-benzodiazepine codependent patients

Shen Y, Huang L, Zou Y, Su D, He M, Fang Y, Zhao D, Wang W, Zhang R

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NaHCO 3 + HCl H 2 CO 3 +NaCl (sodium bicarbonate) + (strong acid) (weak acid) + (salt) H 2 CO 3 + NaOHHCO 3 + H 2 O (weak acid) + (strong base)(bicarbonate) + (water) As with the phosphate buffer, a weak acid or weak base captures the free ions, and a significant change in pH is prevented