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Mass spectrometry analysis was conducted using liquid chromatography-tandem mass spectrometry (LC-MS/MS) identified differentially expressed proteins that were enriched in the ferroptosis pathway and interacted with the SLC3A2 protein (Fig

Mice were anesthetized with ketamine (100 mg/kg) and xylazine (10 mg/kg) by intraperitoneal injection

doi: 10.1073/pnas.0711566105

Foods rich in ellagitannins or ellagic acid If urolithin A sounds like something youre interested in, but you dont want to add another supplement to your daily regimen, then eating foods rich in its precursors could be an option.11 While ellagitannins and ellagic acid can be found in an array of fruits and nuts, the pomegranate fruit (and especially pomegranate juice) is often considered to be their best source.54 Unfortunately, this alternative only has the potential to work if youre part of the roughly 40% or so of people who can produce urolithin A after consuming these polyphenols (this depends on factors like your unique microbiome).6 And, currently, the only way to potentially find out if youre a producer or not is to apply for the Mitopure Challenge offered by Timeline

A novel Wnt pathway inhibitor, SM04690, for the treatment of moderate to severe osteoarthritis of the knee: results of a 24-week, randomized, controlled, phase 1 study