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G.RiveraS.MoonJ.VernetD.RajferJ.Gonzalez-CadavidN

J Clin Endocrinol Metab (2009) 94:1797802

doi: 10.1183/09031936.00.15104100, 7

Excessive iron accumulation in mitochondria causes oxidative stress, generating harmful free radicals that damage DNA, proteins, and lipids, ultimately impairing cardiac function ( / mice exhibited increased expression of mitoferrin 2 (Mfrn2), an iron transporter in the inner mitochondrial membrane