glutathione synthetase deficiency blood smear Erythrocytes Rasburicase-induced hemolytic anemia in previously
Rasburicase induced hemolytic anemia in previously undiagnosed G6PD deficiency Evaluation of Anemia, Leukopenia, and Thrombocytopenia Clinical Tree #imageoftheday, A 24 year old man develops acute jaundice and dark urine after starting trimethoprim sulfamethoxazole. A peripheral smear reveals the specific cellular defects shown. The underlying HEINZ BODIES & BITE CELLS Introduction: Heinz bodies are aggregates of denatured hemoglobin formed after oxidative damage to RBCs. The spleen removes those inclusions, producing bite cells (degmacytes). Classic causes: G6PD Glutamine Synthetase Recombinant Antibody IVD for IHC Zeta Corporation
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