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Therefore, Fe (II/III) and Cu (I/II) are very quick to generate reactive oxygen species after reaction with oxygen (O 2 )

Conclusion & Perspective Alzheimers disease remains one of the great medical challenges: a slowly progressive, multifaceted neurodegenerative disorder for which there is no cure

doi: 10.1530/eje-16-0448 58 PuglisiSRossiniAPoliRDugheraFPiaATerzoloMet al

Effect of Tozasertib on brain tissue 140 levels A marked elevation was noticed in the levels of 140 in ICV STZ-treated mice as compared with vehicle group (Fig