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Postligation Seizures: Cerebrocortical Necrosis This rare and usually fatal complication of shunt attenuation causes generalized seizures 1 to 3 days postoperatively, almost exclusively in cats and small-breed dogs (often in Maltese dogs).31, 100, 118, 119 Its occurrence is unpredictable

Conclusion Biologic therapies represent a promising shift in the management of lumbar disc degeneration by targeting the underlying biological mechanismssuch as inflammation, matrix breakdown, and cellular senescencethat traditional treatments fail to address