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Several mechanisms have been recognized in the development of obesity-induced chronic inflammation including oxidative stress (148, 149), endoplasmic reticulum stress (150, 151), increasing oxygen consumption leading to adipocyte hypoxia (152, 153), inflammasome activation particularly NLRP3 (154, 155), and pattern recognition receptors (PRR) activation and regulation particularly TLR2 and TLR4 activation (156158)

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The role of innate immune cells in the tumor microenvironment and research progress in anti-tumor therapy

Targeting ferroptosis: acteoside as a neuroprotective agent in salsolinol-induced Parkinsons disease models