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Tripeptide-copper complex GHK-Cu (II) transiently improved healing outcome in a rat model of ACL reconstruction

Proteoforms derived from vesicle-associated membrane protein 2 (VAMP2) and VGF were also enriched in males vs females, two proteins which have recently shown secretory interplay 41

Further analysis of signaling pathways confirmed that PD effectively upregulated endogenous TGF-/Nodal signaling and downstream Smad2/3 transduction, while concurrently downregulating BMP signaling, leading to robust DE formation