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Although this was previously attributed to decreased pancreatic insulin secretion and attenuated insulin-mediated hepatic lipogenesis [25], a hepatocyte-intrinsic contribution could not be excluded

However, it only removes subcutaneous fat

It is produced by inflammatory cells and is involved in atherosclerosis formation and levels are associated with increased risk of coronary artery disease and stroke

DOI: 10.1113/jphysiol.1934.sp003147 Gericke A et al (2011): Role of M1, M3, and M5 muscarinic acetylcholine receptors in cholinergic dilation of small arteries studied with gene-targeted mice

Studies such as these will provide a clearer understanding of the importance of these findings on lung disease as a whole, and these will provide the insights needed to convince pharmaceutical companies to sponsor drug trials aimed at specific mitochondrial defects in lung disease