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The deficiency or mutation of the enzyme has been linked with various disease conditions and abnormalities.39 Zmock and Koller associated oxidative DNA damage and subsequent risk of cancer susceptibility in individuals with genetic polymorphisms and altered gene expression/activity in catalase.40 Development of mental disorder has also resulted from polymorphism in the catalase-encoding gene.41 In addition, humans with low catalase levels (acatalasemia) are said to be more predisposed to type 2 diabetes mellitus (Fig

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[145] Tax liability and lobbying [edit] In December 2011, Public Campaign criticized Wells Fargo for spending $11 million on lobbying during 20082010, while increasing executive pay and laying off workers, while having no federal tax liability due to losses from the Great Recession