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Description

Thioredoxin (Trx) is a central reductase with anti-oxidant/anti-inflammatory actions, dysregulated across ALD, NAFLD, and HCC, and often correlating with disease severity [135137]

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10.1016/j.engreg.2025.11.004 242 ZhaoL

Similar to gcn4 deletion, deletion of GCN2 also completely abolished the autophagy flux induced by Vma2 temporal degradation while having only a partial effect on autophagy induced by nitrogen starvation (Fig