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Boroviak, T

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High levels of reactive oxygen species directly sensitize mast cells, altering their intracellular calcium levels and provoking them into inappropriate, constant degranulation

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15 however, when there is a disproportionately high amount of ROS, it induces oxidative tissue damage

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Overlooking arthritis can lead to chronic stiffness

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Proceedings of ASH , abstract 1166 (2007)

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