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developed a cancer vaccine containing six mRNAs with histone stem loops in 3UTR regions, encoding different antigen [311]

Useful as supporting evidence but not diagnostic alone

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Reversibly opening TJs with enhancers remains a strategy actively being pursued,but for the most part enhancers that have reached clinical trials as part of oral peptide formulations seem to have multimodal effects on the epithelium initiated by induction of plasma membrane fluidization

That drop is part of why skin gets thinner, wounds heal slower, and connective tissues lose resilience as we age