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During and after a menstrual cycle, women's bodies have to create new red blood cells

Patients cannot absorb B12 orally, so IM injections are required indefinitely

[DOI] [PubMed] [Google Scholar] 16.Ness-Abramof R, Nabriski DA, Braverman LE, Shilo L, Weiss E, Reshef T, Shapiro MS, Shenkman L

FAQ's of Optineuron Vitamin B &Vitamin B12 Injection: Q: How should I store Optineuron Vitamin B & Vitamin B12 Injection for maximum shelf life

They provide strong proof that a compound has a direct biological effect on the target tissue, but they cannot tell us how that compound will behave when applied to human skin (where absorption, distribution, and metabolism add complexity)