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However, the clinical relevance of these observations has yet to be proved

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27 , 151166.e6 (2018)

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In addition, casein kinase 2, a serine/threonine protein kinase, causes GluN2B endocytosis from synapses through the phosphorylation in the PDZ binding domain of the subunits (S1480) and thus allows synaptic incorporation of GluN2A in rat primary neuronal cultures [142]