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Individuals who benefit most from B12 shots for diagnosed deficiency are patients with conditions that impair gastrointestinal absorption, such as pernicious anemia, tropical sprue, or pancreatic insufficiency

How Vitamin B12 Affects Energy and Sleep Vitamin B12 is known as the "energy vitamin" for a reasonit supports: ATP production in the mitochondria Nerve signaling and mood regulation Cognitive clarity and focus Because of its activating effects, B12 is not recommended close to bedtime