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Weight reduction decreases lean and fat mass, influencing thyroid hormone distribution, and may lower levothyroxine requirements [64]

& Myszkowska-Ryciak, J

Furthermore, recent research suggests that the purinergic receptor P2RX7 plays a pivotal role in the differentiation and maintenance of CD8 + TRM cells

Longer, controlled studies are necessary to determine the duration of effects and to establish appropriate dosing protocols that balance efficacy with safety