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The primary endogenous enzymatic source of O 2 and H 2 O 2 are through the electron transport chain (ETC) in mitochondria and transmembrane NADPH oxidases (NOXs) ( Figure 1 In SLE, ROS play an important role in cellular signaling and are considered hazardous reactive particles to the cells because they damage the intracellular proteins, lipids, and nucleic acids, producing toxic base pairs, leading to DNA damage

Thanks to a revealing podcast chat between Joe Rogan and Kurt Angle, we get a glimpse into personal experiences

This medication works by reducing oxidative stress and inflammation in neurons, which helps improve motor function in some patients

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Different drug compounds are thought to have different modes in DILI pathogenesis, including prompting mitochondrial dysfunction, as part of the characteristic feature of oxidative stress driven toxicity [34, 68]