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The sourcing reality compounds these concerns

Wien Med Wochenschr 144:399406 Holley AK, St Clair DK (2009) Watching the watcher: regulation of p53 by mitochondria

Influence of glycyrrhizin on permeability and elasticity of cell membrane: perspectives for drugs delivery

Pharmaceutics 15:2349

Furthermore, the collagen fragments produced by CAFs can be taken up by pancreatic cancer cells, where they are converted to proline through the action of PRODH1 to support TCA cycle metabolism and cellular respiration [177]