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doi: 10.1038/s41467-020-18525-2 50 HuangZ.HamblinM

Thus, GPx4 not only reduces small hydrophilic peroxides such as H 2 O 2 but also more complex substrates such as phospholipid or cholesterol hydroperoxides even if these are incorporated into membranes or lipoproteins (Ursini et al., 1985