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Without insurance, a months supply is around $800-$900, but with insurance, it can be much lower, depending on your plan

These findings suggest that defects in the remethylation and transsulfuration pathways may contribute to the elevated homocysteine levels observed in children with autism spectrum disorder.35 Epidemiological studies have found that individuals experiencing major depressive disorder and bipolar disorder have elevated plasma levels of homocysteine and deficient plasma levels of folate and vitamin B12.35 The effect of reducing plasma homocysteine levels on the symptomology of these neurological disorders has not been well-studied, and clinical trials investigating associations between folic acid and vitamin B12 supplementation and mood disorders have provided inconsistent results

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No toxic or lethal dose was achieved across a remarkably wide range of doses from 0.006 mg/kg to 20 mg/kg

If folate is lowered due to an MTHFR gene mutation, then you will still absorb B12, but you wont be able to use it properly, which causes the symptoms of B12 deficiency