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If you eat or drink anything other than water before taking the pill, SNAC cannot work properly, and significantly less medication will reach your bloodstream, which can reduce the efficacy

You should discuss B12/MIC use with a healthcare professional to determine which is most appropriate for you

doi: 10.3164/JCBN.22-72 105

This means that it is not possible to overdose on vitamin B12, and as far as we know there is no upper limit on the amount of B12 that can be taken safely by an otherwise healthy person