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10.1016/j.cgh.2014.04.038 176 SahaiA.MalladiP.Melin-AldanaH.GreenR

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Additional metabolic analyses have revealed that oxidative stress induced by the immune response against SARS-CoV-2 infection might impair DNA repair pathways, permanently impacting the health status of these patients [19]

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Moreover, ascorbic acid is essential for collagen biosynthesis in fibroblasts [70]

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By integrating the aforementioned strategies to construct a multi-level, high-precision experimental model system that closely approximates the pathological essence of human GA, we are able to not only enhance our comprehension of disease mechanisms, but also substantially expedite the preclinical advancement and translational headway of innovative therapeutic approaches

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