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doi: 10.1016/j.jddst.2022.103752

This was clearly demonstrated by Giri and coworkers (1984), and similar mechanisms might operate in the spontaneous disease as well (Liu et al

Several studies indicate that the Janus kinase 2 (JAK2)-STAT3 pathway is a crucial mechanism mediating IL-1 release from astrocytes

With all of this taken into account, NVIDIA still allows for more three or four to be used in SLI but they will no longer be recommending gamers use more than two cards, nor will they supporting larger setups on Pascal cards