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Overexpression of miR-339-5p significantly reduced VEGFA protein levels in SH-SY5Y cells, while transfected miR-339-5p inhibitors produced the opposite effects ( Figure 4C )

The percentage of time spent in social approach (sniffing the stimulus animal) and the percentage of time spent exploring the empty chamber were scored using the Observer 3.0 software (Noldus, The Netherlands)

Alternatively, by leveraging the sequence similarity within GST subfamilies, RNA interference targeting entire GST classes could be employed to investigate their roles in ITC detoxification