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Description

These treatment conditions were chosen to mimic excess heme from chronic hemolysis and systemic hypoxic conditions that occur in SCD patients 1,2,11

10.3164/jcbn.18-105

The loading phase front-loads the tissue-repair and copper-peptide exposure, while maintenance tapers frequency once the initial window has passed

Drug-free exosome-loaded MN arrays were used as blank

In this study, significant positive correlations were observed between tryptophan, tyrosine, and xanthine abundances in the EWAT and the relative abundance of Parasutterella in the cecal microbiome (Supplementary Table S5, outliers removed)