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Mater Sci Eng C Mater Biol Appl 109:110645

The sulfhydryl group on the cysteine residue, which is the reactive core of glutathiones antioxidant function, oxidises rapidly under gastric conditions

Mendelian randomization studies show that genetic variants that raise Lp(a) also raise the risk of coronary disease, implying Lp(a) is a causal contributor to CVD