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[DOI] [PMC free article] [PubMed] [Google Scholar] 90.Haibe Y., Kreidieh M., El Hajj H., Khalifeh I., Mukherji D., Temraz S., Shamseddine A

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Researchers associate a vitamin B12 deficiency with various health issues, megaloblastic anemia neurological changes and disorders infertility depression neural tube defects and developmental delays in children born to those with a vitamin B12 deficiency Supplementation may help to reduce the risk of these health issues

Vitamin B12 is best when used in the morning (away from thyroid medication if you are using it)