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Of these 68 drugs, seven (pimozide, furazolidone, perphenazine, bifonazole, disulfiram, clotrimazole and floxuridine) were active as primary hits in the high-throughput screen, and the remaining 61 were classified as inactive as they did not meet the 50% inhibition threshold when evaluated at 10 M

Nigro A, et al

To evaluate the translatability and long-term safety of this approach, we expanded FIX -targeted hepatocytes with Repair Drive, and we followed the mice for 1 year

It also inhibits activation of JAK2/MEK/ERK pathway affecting invasiveness of glioblastoma cells, suggesting anti-metastatic activity of corosolic acid on glioblastoma cells

By modulating the GPX4-GSH axis, KLF11 promotes ferroptosis in lung adenocarcinoma cells, thereby inhibiting cell proliferation and enhancing chemosensitivity (Zhao et al., 2023)