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Xia C, Peng P, Zhang W, Xing X, Jin X, Du J, Peng W, Hao F, Zhao Z, Dong K, Tian M, Feng Y, Ba X, Wei M, Wang Y (2024) Methionine-SAM metabolism-dependent ubiquinone synthesis is crucial for ROS accumulation in ferroptosis induction

This increase the likelihood of B12 deficiency as vitamin B12 is not protected as it passes through the gut

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Digestive conditions like Crohns disease, celiac disease, and chronic gastritis, along with medications such as metformin or acid reflux drugs, can further reduce absorption